ANTIPYRETIC ACTIVITY AND ACUTE TOXICITY OF PHOSPHOROUS CONTAINING SALICYLATES
نویسندگان
چکیده
منابع مشابه
Antipyretic Activity and Acute Toxicity of Phosphorous Containing Salicylates
New phosphorous-containing salicylates and two allyl salicylates with pharmacological potential, derived from salicylic acid, have been synthesized. Their chemical structure has been established by spectral analyses (mass spectra and 1H-NMR). The salicylates presented low toxicity, also showing a remarkable antipyretic activity, greater than that of acetylsalicylic acid (aspirin). Partition coe...
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CIRCADIAN VARIATION OF THE ACUTE TOXICITY AND NOCICEPTIVE ACTIVITY OF AMINOPHYLLINE IN MICE
The circadian variation of the toxicity and nociceptive actIvity of aminophylline as an important methylxanthine was studied in mice. The animals were housed under controlled light-dark cycles for at least 2 weeks. Acute toxicity was determined by LD50. Hot-plate test was used for determination of thermal pain threshold. Doses of 200, 250, 280 and 340 mg/kg of aminophylline were injected i...
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The active principles of brown alga, Turbinaria conoides (J.Agardh) Kuetz. (Sargassaceae) was extracted with n-hexane, cyclohexane, methanol and ethanol-water (1:1) and investigated for acute toxicity and antipyretic activity. Phytochemical analysis of the extracts revealed the presence of steroids, flavonoids and reducing sugars. Acute toxicity study was performed in Wistar rats after administ...
متن کاملAntidiarrheal activity and acute oral toxicity of Mentha longifolia L. essential oil
Objectives: Mentha longifolia L. (Lamiaceae) is an annual herb that is used in the Iranian traditional medicine for treating stomach and intestinal disorders. The purpose of this study was to determine the protective effect of M. longifolia on experimental diarrhea in a rat model. Materials and Methods: The antidiarrheal activity of essential oil of M. longifolia (20-80 mg/kg) was investigated ...
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ژورنال
عنوان ژورنال: Malaysian Journal of Science
سال: 2014
ISSN: 1394-3065
DOI: 10.22452/mjs.vol33no1.12